Article Dans Une Revue Current Medical Research and Opinion Année : 2024

Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review

Résumé

Fexofenadine is a second-generation inverse agonist of H1-receptor of histamine which is highly selective with proven efficacy in relieving symptoms associated with allergic conditions. It has an additional benefit of not penetrating the blood-brain barrier and therefore do not induce sedation and not impair the cognitive function/psychomotor performance. This review aimed at providing evidence based on available controlled studies to reinforce the non-sedative property of fexofenadine for treating patients with allergic rhinitis and urticaria.
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hal-04920792 , version 1 (30-01-2025)

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Ignacio Ansotegui, Jean Bousquet, Giorgio Walter Canonica, P Demoly, Rene Maximiliano Gómez, et al.. Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review. Current Medical Research and Opinion, 2024, 40 (8), pp.1297-1309. ⟨10.1080/03007995.2024.2378172⟩. ⟨hal-04920792⟩
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